Getting Ready for Number Four

I talked last week about going back to work. I think I’ve been premature. At times I think I’m ready and I am bored and want to be at work but at other times I get nervous about future chemo treatments. I know that the effects can be cumulative. I already feel I won’t be able to put in my full hours during chemo week. If I stay out a few more weeks I will have LTD to fall back on when I can’t work. That will help me until the end of chemo. Hopefully, things will be better by then and I can come back to work full time and feel good about it.

It was a big decision and I stressed over it all week but I can’t in good conscience give up the LTD option.

******** WARNING TMI PARAGRAPH *************************************

Last week I worked three days and was terribly constipated the entire time. I won’t go into too much detail about fixing the issue, just say I used every laxative at my disposal for several days and in the end my fix involved a rubber glove and a soaped finger. After things were fixed I felt like I was anally compromised by a Mack truck.. from the inside out.


I did have some really annoying cold sensitivity off and on at the beginning of last week but it has disappeared this week.

I have chemo number four tomorrow. When it’s done I’m 1/3 of the way through. YIPPIE.

I want to talk to the onc’s office about cimetidine, which is basically Tagamet. There are studies that show that this can inhibit in vivo growth of human colon cancer. Melatonin is another supplement I want to discuss. Again there have been some studies that show that it can induce cell death in cancer cells.

The last thing I wish to discuss with the doc is cannabidiol or CBD.  Studies have found that CBD, a nonpsychoactive component of the marijuana plant, is a potent inhibitor of breast cancer cell proliferation, metastasis, and tumor growth (along with other metastatic cancers).  Unfortunately, Wisconsin is not a medical marijuana state and CBD is still considered part of a schedule 1 drug and is not legal for use even though it is nonpsychoactive. Please click on the first link in this paragraph for the pertinent information.

One thing I did want to share with any readers I have is a predictive tool found on Memorial Sloane Kettering’s site. MSK is one of the top cancer centers in the country. This tool is called a Nomogram. I fill in the information from my pathology and surgery reports (one item I’m not sure about) and this tool is meant to show probabilities of being disease-free five and ten years after surgery based on the information I fill in. This is not probabilities of mortality, it is probabilities of recurrence.

If I assume the one item I’m not sure about is positive, I show a 1 in 3 chance of being disease free still in five years and a 1 in 4 chance of making it to ten years disease free. If I assume the item I’m not sure about is negative then my numbers jump to 1 in 2 for five years free and 1 in 3 for ten years. These are all odds of being found NED (no evidence of disease) that I will gladly take.  Mayo’s Adjuvant Tools give different but better numbers.

For anyone wanting to play around with my numbers, I am 52, tumor was in sigmoid colon, my CEA was 90 but tool only allows a high of 64, TNM stage was T3, differentiation was moderate, I had 0 positive nodes out of 7, there was perineural invasion and I’m assuming positive on vascular involvement, and I am in chemo after surgery.


Asgara Queen of Confused


2 responses to this post.

  1. I am always betting on you being NED because you are 1 in a million!

    I think that the decisions about work, while difficult are correct – you are not doing yourself or for that matter your office any good if you are not truly feeling up to it or having dire consequences. From what I have seen of your officemate’s comments they sound like a very caring and supportive lot who understand just how huge this is to be going through!

    Lastly – I know that Tagamet is hugely helpful in canine cancer treatment. After the last time Sophie had cancer surgery the doctor had her on a course of it (In addition to the benadryl which was an inhibitor or the MAST cell cancer) because, to dumb it down, it apparently keeps free roaming cancer cells from ‘sticking’ especially within the gastric system. IDK How this parallels the human situation – but I figured I’d give you what little experience with it I had to add to your pile. 😉
    /love Cynnialuna.. princess of loserville


    • Drop the Princess of Loserville hun, Cynnialuna is the Bouncing Boomkin Extraordinaire! Just be careful, if…when… you come visit as I still have my Boomkin Suppression Kit sitting out on my desk! PINK DUCT TAPE FTMFW


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